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Portland Mayor Keith Wilson said the shooting is "deeply troubling" on the heels of the death in Minneapolis.

"We cannot sit by while constitutional protections erode and bloodshed mounts. Portland is not a 'training ground' for militarized agents, and the 'full force' threatened by the [Trump] administration has deadly consequences. As Mayor, I call on ICE to end all operations in Portland until a full investigation can be completed," said Wilson.

"Federal militarization undermines effective, community‑based public safety, and it runs counter to the values that define our region. I will use every legal and legislative tool available to protect our residents' civil and human rights."

Portland has been one of several Democratic cities in the U.S. Subject to the Trump administration's immigration crackdown.

The statement from the Portland Police Bureau said officers responded to reports of a shooting on Southeast Main Street just after 2:15 p.m. PT.

Less than 10 minutes later, officers found a man and a woman with gunshot wounds at NE 146 Avenue and East Burnside Street, nearly five kilometres away from where the shooting took place.

The man and the woman were both taken to hospital, police said.

Reuters

U.S. Federal agents shot two people in Portland, Ore., this afternoon, police said, adding that they were taken to hospital and their conditions were not known.

An ABC News affiliate reported that the agents involved in the shooting were U.S. Customs and Border Protection (CBP) agents and the FBI was leading a probe. CBP and ICE both fall under the U.S. Department of Homeland Security.

"Their [people who were shot] conditions are unknown. Officers have determined the two people were injured in the shooting involving federal agents," the Portland Police Bureau said in a statement.

"We understand the heightened emotion and tension many are feeling in the wake of the shooting in Minneapolis, but I am asking the community to remain calm as we work to learn more," Police Chief Bob Day said.

The statement said city police were not involved in the incident.

The Associated Press

Multiple faith ministries came together earlier today to hold a vigil at the site, said minister JaNaé Bates Imari, one of the organizers. She said Minnesota is a "state that feels very much under siege right now."

"We all deserve to have dignity and humanity recognized," she said.

She said faith leaders have called for the officer involved to be prosecuted, for ICE to leave the state and for Congress to provide oversight and accountability.

I'm reporting from Minneapolis. I'm at the site of the memorial for Renee Good, where the shooting happened yesterday.

Swarms of people have been coming and going today, but some are planning to stay longer.

A group called the Autonomous Yurt Union came out to build a Mongolian-style yurt here. The group builds yurts throughout Minneapolis to provide temporary shelter for unhoused people.

Alex Johnson, who is part of the group, says he wanted to help keep people safe and warm in case the site becomes an encampment.

He says the yurt can house 20-30 people at a time.

And now, with the rain pouring down, protesters and members of the community are making good use of the shelter.

In general, Gross said law enforcement officers are trained to not shoot at a vehicle that is coming toward them and are instead told to try to get out of the way.

That's because shooting at the driver won't stop the vehicle from moving toward them, Gross said. Also, if the driver is struck, they're likely to become incapacitated, lose control of the vehicle and crash, "potentially killing or seriously injuring someone else or causing property damage," he said.

"And that's exactly what happens in this case," Gross said, alluding to video footage that shows Good's SUV crashing into another vehicle after the shots are fired.

John Gross, associate professor of law at the University of Wisconsin, has experience analyzing photographic evidence and has written extensively about police use-of-force policies, including shooting on vehicles.

Having watched various videos of the fatal shooting, Gross said it does seem the victim didn't comply with officers' demands to step out of her vehicle and may have been deliberately blocking the road.

But if there is an indication the victim was trying to use her vehicle as a weapon — as federal officials have alleged — Gross said it "certainly doesn't appear on the video."

He said video shows the officer at the side of the vehicle when he fires the first shot, not at the front, and he fires two more shots as the vehicle is turning away from him.

"The idea that the vehicle was being used as a weapon or was targeting the officers, I mean, it's clearly not supported by the video evidence that we have from the scene."

Edwin Torres DeSantiago with the Immigrant Defense Network says his organization has been documenting how immigration agents have been operating in Minnesota, including "many, many" instances where they have been in plain clothes or unmarked vehicles.

Agents have been showing up "everywhere," including hospitals, schools, daycares and churches, he said.

"Every single aspect of an individual's life is being dissected, so you can feel like you're constantly being watched and targeted," he said.

"That is not normal. And that level of chaos needs to stop."

A Minneapolis woman says she and her husband had an encounter with a gun-wielding ICE agent roughly 30 minutes before Good was killed yesterday.

"We wanted them to do a U-turn and drive back out the same way that they came," Miller said. "Instead, the driver of that vehicle opened the driver's door, pulled out a gun and told my husband to move the car. So he did."

Miller says she and her husband arrived at the scene of the Good’s shooting shortly after, where they heard a woman screaming: "You just shot her!"

Minneapolis Mayor Jacob Frey is again calling federal officials' version of yesterday's events "bullshit" in a post to X this afternoon, specifically calling out the U.S. Secretary of Homeland Security.

"Let's call a spade a spade: Kristi Noem watched the videos and doesn't want an impartial investigation because she knows her narrative about domestic terrorism is bullshit," Frey's post says.

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